PHOENIX -- Miami center fielder Marcell Ozuna hit a two-out, two-run home run in the ninth inning to ruin left-hander Vidal Nuno's Arizona debut in the Marlins' 2-1 victory over the Diamondbacks on Tuesday at Chase Field.

Arizona closer Addison Reed (1-5) walked Ed Lucas to open the ninth but got the next two batters before Ozuna hit a 2-2 fastball into the camera well located in the batter's eye in center field.

Reed has five blown saves, tied for the National League lead, in his first season in Arizona. He has three in the last 13 games.

Mike Dunn (7-4) struck out the only batter he faced for the victory, and Steve Cishek recorded his 20th save.

Nuno threw seven scoreless innings and scored the Diamondbacks' only run. He gave up three hits and struck out a career-high seven while retiring 17 of the final 19 batters he faced. He did not allow a runner past second base.

Nuno was obtained from the New York Yankees for right-hander Brandon McCarthy on Sunday. McCarthy was 0-6 with a 5.37 ERA in 10 starts at Chase Field this season.

Miami left-hander Brad Hand gave up seven hits and one unearned run in 6 1/3 innings on the third anniversary of his only major league victory as a starter, beating Houston on July 7, 2011. He is 2-11 in his career.

Third baseman Martin Prado and catcher Tuffy Gosewisch had two hits apiece for Arizona (38-54), which had a two-game winning streak broken.

Ozuna extended his hitting streak to 14 games with two of five hits for the Marlins (44-46), who have won three of their last four.

Third baseman Casey McGehee had a career-high 14-game hitting streak and a major league-long 21-game road hitting streak broken.

Nuno reached on a fielding error by McGehee to open the fifth inning and took second on center fielder Ender Inciarte's bunt single past the mound. Second baseman Aaron Hill singled to left to break the scoreless tie.

Hand got out of the inning on a double-play grounder and a groundout.

Miami had three hits in the first six innings, first baseman Jeff Baker's one-out double in the second inning, Ozuna's two-out double in the fourth and Christian Yelich's leadoff single in the sixth. Each runner was unable to advance.

NOTES: Miami 3B Casey McGehee entered the game with a .416 career batting average against the Diamondbacks, the second-best career average among active players against any one team. Yankees 3B Alex Rodriguez is hitting .432 against San Francisco. ... Arizona RHP Bronson Arroyo said he will use Diamondbacks physicians Dr. Michael Lee and Dr. Donald Sheridan for his Tommy John surgery, which he will have either July 15 or July 16. ... Arizona LF Mark Trumbo has three home runs in his first give games of a rehab assignment after a grand slam at Triple-A Reno on Monday. Trumbo, who has been out since April 24 with a stress fracture in his left foot, is unlikely to be activated before the All-Star break, Arizona manager Kirk Gibson said, because the Diamondbacks don't want him idle for four days during the break next week.